Penn State led 28-20 with less than two minutes to go, but a late touchdown drive orchestrated by Indiana quarterback Michael Penix Jr. forced overtime, where the Hoosiers prevailed 36-35.
Penn State running back Journey Brown, the Nittany Lions' leading rusher last year, could miss the 2020 season while undergoing treatment for a medical condition discovered during the offseason.
Nick Saban received three negative COVID-19 tests in three days, clearing his return to the sideline for his Crimson Tide's clash with No. 3 Georgia Saturday night.
Minnesota wide receiver Rashod Bateman will be back to play for the Gophers this fall, but Penn State linebacker Micah Parsons won't be returning to the Nittany Lions.
The Mid-American Conference will play a six-game football season beginning Nov. 4, which means all 10 Football Bowl Subdivision conferences will end up playing football this fall.
With Ohio State set to start its season against Nebraska on October 24, Fox's Big Noon Kickoff experts, Urban Meyer and Reggie Bush, like the Buckeyes to win it all.
Dabo Swinney made it clear that he didn't think college football needed the Big Ten, saying "the last time I checked there’s been a lot of champions come from conferences that were already playing."