Michigan has opened as a 3.5-point favorite for Saturday's rivalry game at Ohio State, according to Vegas Insider.
It marks the first time since 2011 that Ohio State will be an underdog for The Game, and the first time since 2004 that the Wolverines are favored over Ohio State for a game in Columbus.
Both teams hold 10-1 records entering this week's game, and the winner of Saturday's game will be this year's winner of the Big Ten East. Ohio State has been the dominant team in the rivalry since Urban Meyer became the Buckeyes' coach, winning six straight games against Michigan.
Even so, the Wolverines – who are currently ranked No. 4 in both major polls and the College Football Playoff standings – are favored to turn the tables this year against Ohio State, who is currently ranked No. 10 in both major polls and the playoff standings.