Ohio State opened as a 15-point favorite over Nebraska, according to Vegas Insider, with game time set for 7:30 p.m. ET in Lincoln this Saturday night.
The Buckeyes, who are now 4-0 this season with a 3-1 record against the spread, are coming off a 71-point win over Miami (Ohio) on Saturday in a game they were favored to win by 39 points.
Nebraska is coming off a 42-38 victory over Illinois in Champaign thanks to a strong fourth quarter in which the Cornhuskers outscored the Illini 15-3.
On the season, Nebraska boasts a 3-1 record with the only blemish coming on the road to Colorado, 34-31.
College GameDay will be on location in Lincoln on Saturday and ABC has your television coverage.