2022: Just feels like a major wasted opportunity. Get through Georgia and osu beats TCU. I feel pretty certain about that. 
2019: The Clemson loss in 2019 was very rough but osu would’ve had to play a historic offense in LSU. 
-2015: OSU misses the playoffs but probably had the best team in the country. 
-2012: Urban’s undefeated team that was banned from the National Championship game. No doubt they beat ND that season. 
-1996 and 1998. OSU had the best team in the nation both years and lost very close games to Michigan and Sparty. 
 

Those to me are the most disappointing losses osu has had in recent memory.