| SAT SEP 13 1:30 PM |
 SYRACUSE
|
OHIO STADIUMCOLUMBUS, OH | NONE |
W, 31–21
|
| SAT SEP 20 1:30 PM |
 MINNESOTA
|
OHIO STADIUMCOLUMBUS, OH | ABC |
W, 47–0
|
| SAT SEP 27 1:30 PM |
 #20 ARIZONA STATE
|
OHIO STADIUMCOLUMBUS, OH | NONE |
W, 38–21
|
| SAT OCT 4 1:30 PM |
 #11 UCLA
|
OHIO STADIUMCOLUMBUS, OH | ABC |
L, 0–17
|
| SAT OCT 11 2:00 PM |
 NORTHWESTERN
|
DYCHE STADIUMEVANSTON, IL | NONE |
W, 63–0
|
| SAT OCT 18 1:30 PM |
 INDIANA
|
OHIO STADIUMCOLUMBUS, OH | NONE |
W, 27–17
|
| SAT OCT 25 2:30 PM |
 WISCONSIN
|
CAMP RANDALL STADIUMMADISON, WI | NONE |
W, 21–0
|
| SAT NOV 1 1:00 PM |
 MICHIGAN STATE
|
SPARTAN STADIUMEAST LANSING, MI | NONE |
W, 48–16
|
| SAT NOV 8 1:30 PM |
 ILLINOIS
|
OHIO STADIUMCOLUMBUS, OH | NONE |
W, 49–42
|
| SAT NOV 15 2:00 PM |
 IOWA
|
KINNICK STADIUMIOWA CITY, IA | NONE |
W, 41–7
|
| SAT NOV 22 12:30 PM |
 #10 MICHIGAN
|
OHIO STADIUMCOLUMBUS, OH | ABC |
L, 3–9
|
| FRI DEC 26 3:00 PM |
 #10 PENN STATE 1 |
SUN DEVIL STADIUMTEMPE, AZ | NBC |
L, 19–31
|
- 1980 FIESTA BOWL ↑
