I look at this schedule (especially the conference schedule) a few different ways...
1) The teams OSU play twice are probably the most winnable this season. That is good for accumulating wins, but isn't the most helpful for SOS.
2) The teams OSU only play once in conference and on the road are probably the top teams in the B1G this season. It will be more difficult to win those games, but any win against those teams will be huge road wins and help SOS/RPI/BPI and all those metrics.
Overall, OSU's schedule is much tougher this year than in year's past. The non-conference schedule includes more high-major conference teams, and more chances for good wins. It is unfortunate it happens this year with a slimmed down roster, but maybe Holtmann can produce some magic with this group. The opportunities are there!