I hear you on ND/Pitt and USC/Colo (the OP was stretching on those), but I can't believe you're not seriously interested in the MSU/PSU and UM/Wisky games. Those are two of the biggest B1G games of the year. If you really don't care about those games, then I think what you're saying is that you only care about the games that are top 10 matchups. And if that's the case, I think it's fair to say that you're just not a big CFB fan. That's ok, I'm not trying to be critical, but if top 25 matchups with conference championship implications aren't interesting to you, then you're right, there aren't many games each week that are going to keep your attention.
That said, I'm not sure how the NFL would meet your need. I'm not even sure who the top teams are, as the NFL is as muddled as ever, so it's hard to identify huge matchups. Some would say that's an argument in favor of the NFL v. CFB (parity and turnover of playoff teams each year), but if it's big games you're looking for, the NFL has fewer than CFB. Frankly, I don't know what I'd call the biggest NFL game of the year so far, but I'm certain it wasn't as big as OSU/PSU, Auburn/Wash, ND/Stanford, or many others.