If you look at the offensive play chart you can see that there is some confusion about identity and how to use the weapons available.
Offensive football is about stringing first downs together in order to drive the field to score a FG or TD. You can negate the need for efficiency at getting 1st downs through explosive plays. The better offenses go 75 yards in 10+ plays AND supplement that ability with explosive plays.
Against Indiana, Ohio State had one sustained drive the entire game vs. a shoddy IU defense. That drive resulted in 3 points. They had one drive of 4 plays gaining 4 yards that resulted in another FG. The rest of their scoring and productive offense was produced in 4 explosive plays: 3 EE runs and a 23 yard reception by Mike Thomas. Relying on explosive plays gets you beat the first time a defense can hold you to one or two of them.
Here's what I saw that contributes to the inefficiency:
14 runs for negative or 0 yards --- 3rd down passing: 3/6 for 0 first downs --- 1st Qtr/2nd series: on 3rd and 2 QB draw for no gain --- 1st Qtr/3rd series: on 1st and 10 Taylor Decker gets beat by edge rusher, CJ is hit and fumbles, OSU recovers for a loss of 8. On 3rd and 3 CJ scramble nets -2 yards --- 2nd Qtr/1st series: On first down CJ keeps on the lateral speed option (which they should never run unless he pitches) for a net -1 yards -- 2nd Qtr/2nd series: pass complete to J Marshall for 28 yards, but fumbles. IU recovers --- 2nd Qtr/3rd series: CJ pass to M Thomas inaccurate to prevent a TD followed by CJ pass to J Marshall inaccurate to prevent TD --- 2nd Qtr/4th series: 13 yard TD pass to EE negated by Braxton personal foul blocking penalty. On next play CJ holds the ball for 8 seconds and is sacked. On 3rd down CJ not ready for snap and fumbles for a loss of 4, but the play is negated by illegal shift forcing 4th down and a FG attempt that was missed. --- 3rd Qtr/3rd series: On 2nd and 10 CJ pass behind J Marshall on slant, incomplete. On 3rd and 10 CJ pass to M Thomas is deflected by C Samuel, incomplete. --- 3rd Qtr/4th series: On 2nd and 7 bad snap on QB draw, timing off, loss of 5 yards. On 3rd and 12 CJ throws interception at the IU 12 yard line and returned to the IU 45. --- 3rd Qtr/5th series: On 2nd and 6 CJ keeps the ball on a READ OPTION (WTH?) for a loss of 2 yards. --- 4th Qtr/2nd series: On first play CJ completes pass to J Marshall for 12 yards, but he fumbles and IU recovers. --- 4th Qtr/4th series: Ohio State will not throw the ball across the LOS the rest of the game (10:00 left). Before 1st play OSU has to call a timeout because the play clock was running out and they were disorganized.
Within the above paragraph is a sketch of the dysfunction. I'm not smart enough to assign specific blame to specific people, but that is a dumpster fire.