A lot of this is due to MSU's scheme and how they are set up to stop short and intermediate routes, particularly to the middle of the field. I've written about this a couple times, and trust me, the OSU fan base is far from the first and won't be the last to leave fans wondering "why didn't we attack the short middle with quick throws like slants?"
The way MSU plays with their OLBs, they pretty literally catch any receiver trying to cross and wall off the middle of the field. So any release off the LOS that is initially inside will get caught. On the outside the tend to press with an inside technique. My impression from the game was that MSU's technique was on a different level, and in that instance it really helps because it forces any inside release to initially work parallel to the LOS. On top of that, it makes things like bubble screens extremely difficult, especially with the way MSU plays their safeties over the #2 about 8 yards off the ball and flashing down on first movement.
What this means is that there are really two open areas of the field, you have the short/intermediate out from the #2 or #3 receiver, which is still a long pass that will be contested by a DB (how MSU has been playing the coverage lately) and you have the one on one match-ups deep.
Now, someone was talking about the TE/WR seam from the #2 that was working all day. I haven't watched the 2nd half again but I'm certain MSU made an adjustment to make this throw more difficult. Likely they went to a cage or jam shade (this means the DE lines heads up on the TE or OT) to the initial RB side. This does two things: 1) it puts another DL in the belly run play; 2) it allows the OLB to go out further over the #2 and carry his route (therefore slowing him down). The second point is allowed to happen because the OLB now has outside leverage as his assignment, it also allows the safety more free will to play run and recover on that seam, which wasn't the case in the 1st half and start of the 2nd half when MSU was simply splitting the difference with the OLB or giving a free release to the #2. My guess is this is also why you started seeing more of Miller running than giving to Hyde, as the OLB was initially occupied by the #2 allowing Miller to work in space.
Again, I haven't watched the 2nd half film, but this is a common way for MSU and Narduzzi to adjust within their cover 4 scheme to take away some of the things OSU wanted to do on offense.
Lastly, to fit some of the offensive playcalling complaints: there is a triangle that is set up when looking how to call plays. One point is taking what the defense gives you (spread teams tend to lean in this direction); another point is doing what you do best (this is more a pro-style philosophy); another point is sticking with your intended game plan that you worked to draw up for a week. Now, this isn't an isosceles triangle, but still, you walk a fine line with how you call the next play. Lean too much one way and the play still has perfectly good logic, but isn't the right call. And so you work within that triangle trying to find the right balance of each. IMO, they went too far away from what was working (feeding Hyde) regardless of MSU's adjustments.