Yes and no. During any running play the defense will have at least a +1 numerical advantage (b/c the ball carrier's defensive counterpart will always be unblocked). In a more traditional offensive scheme that number increase to +2 because the QB hands the ball off and doesn't block anyone. However with a read option play one player is "blocked" by the QB's read and the defense is back to +1.
With a triple option that doesn't change the fact that the defense has a +1 advantage. The main difference is which defenders are read. During the triple the QB reads one defender and pitches off another. Because both defenders are on the play side the offense has a 3 vs 2 fast break. Compare to a zone read where the QB reads a defended on the backside of the play. In short the offense does not gain the same blocking advantage that the triple does. If you ask old school triple option coached they will tell you the zone read isn't even a real option play. This doesn't really apply to inverted veer or power read play since it reads a play side defender.
Sorry for the long post I hope it helped clear things up.