I'm not sure what "2 best players" you are referring to, but Jae'Sean was the best player on the floor all season for OSU. KBD missed all but 3 or 4 games and he was our best player coming into the season. With those 2 back and fully healthy I see no reason why OSU won't finish at least in the upper half of the B1G.
TT was good, but he didn't exactly have a breakout year. Same for Lyle. I do think we will miss Lyle, he could go off for 25 on any given night (and struggle too) but if for nothing else, depth. But this isn't anywhere near as bad as things were when O'Brien took over, or when Matta took over.